3D atlas merges brain dissection and imaging for detailed white matter mapping

BraDiPho (Brain Dissection Photogrammetry) is an innovative tool for the study of white matter connections in the human brain. The realistic map was developed by a group of researchers from the University of Trento, the Provincial Healthcare Service of Trento, Fondazione Bruno Kessler and the Universities of Bordeaux and Sherbrooke.

The published paper reports on the results of more than 5 years of collaboration and introduces a new instrument that the scientific community can use to accurately integrate ex-vivo dissection and in-vivo tractography data. These two complementary techniques have never been integrated so far into the study of human white matter connections, and this confirms a new research trend where multidisciplinary competencies converge, in this case clinical neuroscience and artificial intelligence.

The study opens new frontiers for neurosurgery in the treatment of brain tumors and the approach to degenerative neurological disorders, and in neuro-rehabilitation to harness the potential of brain plasticity.

BraDiPho was presented in a paper published in Nature Communications, with Laura Vavassori as first author. She is a doctoral student at the Center for Brain/Mind Sciences (Cimec) of the University of Trento.

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