CAESAREA, Israel, June 9, 2025 /PRNewswire/ — IceCure Medical Ltd. (NASDAQ: ICCM) (“IceCure”, “IceCure Medical” or the “Company”), developer of minimally-invasive cryoablation technology that destroys tumors by freezing as an alternative to surgical tumor removal, today announced it has received a Notice of Allowance from the United States Patent and Trademark Office for its patent application titled ‘Cryogen Flow Control’. Once granted, the patent will be in effect until 2045. A patent has already been granted for this invention in Japan and is pending approval in European Union and other major markets.

“This invention is designed to further improve cryoablation’s efficiency and to expand the number of indications we can deliver in the future,” stated Eyal Shamir, IceCure’s Chief Executive Officer. “As we await the U.S. Food and Drug Administration’s (“FDA”) decision on marketing approval for ProSense® in early-stage breast cancer when combined with adjuvant endocrine therapy for women aged 70 and over, expanding our intellectual property assets around our platform cryoablation technology is more important than ever. We believe IceCure is the global leader in liquid nitrogen-based cryoablation technology as we continue to innovate and roll out our systems commercially.”