A light-based modulation tool for brain plasticity opens promising avenues for treating Huntington’s disease

Synaptic plasticity—the brain's ability to modify the connections between neurons to support learning—is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.

The study, published in the journal iScience, is led by Mercè Masana, professor at the UB’s Faculty of Medicine and Health Sciences and researcher at the Institute of Neurosciences (UBneuro), the August Pi i Sunyer Biomedical Research Institute (IDIBAPS), and the CIBER Area for Neurodegenerative Diseases (CIBERNED).

Researchers from the University of Vic-Central University of Catalonia (UVic-UCC), the Navarrabiomed Proteomics Platform, Aston University (Birmingham, United Kingdom), the University of Oulu (Oulu, Finland), the Vision Institute (Paris, France), and the University of Bayreuth (Bayreuth, Germany) also participated in the study.

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