AI tool mimics pathologists to improve breast cancer tissue analysis accuracy

A research team led by two University of Maine Ph.D. students developed an artificial intelligence (AI) system that could make it easier and faster for doctors to identify signs of breast cancer in tissue samples, possibly preventing delays and saving lives.

The system, named the Context-Guided Segmentation Network (CGS-Net), mimics the way human pathologists study cancer tissue to achieve accuracy in digital cancer diagnosis. Spearheaded by Jeremy Juybari, a doctoral candidate in electrical and computer engineering, and Josh Hamilton, a doctoral candidate in biomedical engineering, the tool introduces a deep learning architecture designed to interpret microscopic images of tissue with greater precision than conventional AI models.

Breast cancer is the second leading cause of cancer-related deaths in women, affecting one in eight over their lifetime. Diagnosis still relies on the microscopic inspection of chemically stained tissue samples, a process that requires expertise and time.

Two-thirds of the world’s pathologists are concentrated in only 10 countries, leaving large regions facing diagnostic delays that contribute to preventable deaths. In India, for example, roughly 70% of cancer deaths are linked to treatable risk factors compounded by limited access to timely diagnostics.

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