MedTech News:

Andrew Celentano

Bladder cancer detected up to five years before diagnosis—thanks to AI

Bladder cancer claims 220,000 lives globally each year, with symptoms sometimes mistaken for other conditions such as kidney stones. Now researchers have developed an artificial intelligence system that can identify bladder cancer patients up to five years before their official diagnosis, potentially revolutionizing screening for the disease.

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A painless punch with a microneedle patch could detect kidney disease earlier

Kidney disease is silent in its early stages, progressing without symptoms until the disease is advanced. Researchers in the McKelvey School of Engineering at Washington University in St. Louis, in collaboration with researchers at WashU Medicine and Texas A&M University, have been developing a minimally invasive method to improve diagnosis at earlier stages.

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New mRNA immunotherapy eliminates pancreatic tumors in mice

Inspired by the work of the RNA Therapeutics Institute at UMass Chan Medical School and the development of the COVID vaccine, Marcus Ruscetti, Ph.D., and Chaitanya Naimesh Parikh, Ph.D. ’26, have developed an immunotherapy using a cocktail of messenger RNAs (mRNA) that could potentially transform pancreatic cancer treatment.

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Dual therapy activates immune defenses while damaging lung cancer DNA

A new preclinical study has demonstrated that combining HER3-DXd with olaparib significantly improves treatment responses in lung cancer models. This combination therapy induces irreparable DNA damage in cancer cells while also stimulating the body’s immune system to combat the disease. The research is published in the journal Cell Reports Medicine.

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