Burn injuries are a kind of severe trauma, which often involves multiple organs, causing high morbidity and mortality. During burn debridement, hemostasis control has long been challenging. Traditional electrocautery is effective for bleeding control, but it carries risks such as thermal tissue damage and it has operational limitations.
BC has emerged as a promising wound dressing material due to its microporous structure, mechanical strength, breathability, and biocompatibility. However, BC lacks intrinsic bioactivity, especially hemostatic properties, limiting its effectiveness in complex wound situations.
In this study, the researchers, led by Dr. Zhong Chao and Dr. An Bolin from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, collaborating with Dr. Liu Yan from Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, developed a synthetic bioengineered solution.