Neurological diseases affect millions worldwide, and the need for long-term patient-friendly treatments has never been greater. While needle-based injections are the standard for most therapies, regular drug injections can often be painful and inconvenient. Microneedles—which are tiny, micron-sized needle systems—have emerged as a promising alternative to conventional needles and offer a pain-free way to deliver medications. However, most existing microneedles are rigid and can cause discomfort during prolonged use, therefore limiting their adoption in long-term treatment.

To overcome this, researchers from South Korea have designed a new microneedles system inspired by the natural mechanism of a bee sting. Led by Professor Wonku Kang and colleague Dr. Sohee Jeon from the College of Pharmacy, Chung-Ang University in collaboration with Dr. Jun-Ho Jeong from College of Medicine at Chung-Ang University, the team introduces wearable “Electrospun Web Microneedle (EW-MNs)” based patches which enable long-term and continuous drug delivery through the skin. The study was made available online in Advanced Healthcare Materials on July 31, 2025.