MedTech News
.................... by Andrew Celentano
‘Teacher cells’ coated with tumor fragments train T cells to attack cancer in lab tests
The immune system possesses legions of T cells that, if primed, could hunt down and destroy tumors. Now, a UC San Francisco team has invented a way to do this by combining immune cells grown in the lab with samples from a patient’s tumor. Like giving a scent to a hound dog, it shows the immune system how to go after the cancer.
New mRNA immunotherapy eliminates pancreatic tumors in mice
Inspired by the work of the RNA Therapeutics Institute at UMass Chan Medical School and the development of the COVID vaccine, Marcus Ruscetti, Ph.D., and Chaitanya Naimesh Parikh, Ph.D. ’26, have developed an immunotherapy using a cocktail of messenger RNAs (mRNA) that could potentially transform pancreatic cancer treatment.
Unravelling a New Mechanism of PARP Inhibitor Resistance in Cancer
The research highlights the role of TEX264, a protein that helps cancer cells remove and degrade PARP1 trapped on DNA following treatment
Avulux lands FDA de novo classification for light-sensitive migraine lenses
Avulux’s lens technology uses a optical filters to block up to 97% of blue, amber, and red light while letting soothing green light through.
Olympus launches new flexible-tip videoscope
Olympus Corporation has announced the launch of the ENDOEYE FLEX 3D flexible-tip videoscope, compatible with the VISERA ELITE III surgical imaging platform to support more efficient, high-quality endoscopic surgery.
Dual therapy activates immune defenses while damaging lung cancer DNA
A new preclinical study has demonstrated that combining HER3-DXd with olaparib significantly improves treatment responses in lung cancer models. This combination therapy induces irreparable DNA damage in cancer cells while also stimulating the body’s immune system to combat the disease. The research is published in the journal Cell Reports Medicine.
Altered ribosomes help explain how an enzyme fuels tumor growth
A new Northwestern Medicine study has identified a previously unknown mechanism by which an enzyme promotes cancer cell proliferation, establishing it as a promising therapeutic target for cancer, according to findings published in Nature Communications.
Researchers uncover brain-network dynamics in schizophrenia
Researchers at Georgia State University have identified a previously unknown aspect of schizophrenia that offers a new way to understand how the disorder affects large-scale brain coordination. In a new study, published in the journal Translational Psychiatry, researchers introduced a method for measuring how brain networks maintain balanced activity and recover when that balance is disrupted.