The study, published in Advanced Science, was led by Youping Deng, Ph.D. candidate Zhuokun Feng and Masaki Nasu from the Department of Quantitative Health Sciences at the UH Mānoa John A. Burns School of Medicine. Deng also co-directs genomics research at the UH Cancer Center. UH Cancer Center researcher Loïc Le Marchand, lead investigator for the Multiethnic Cohort (MEC) Study, served as co-author.
“A central question in this study was whether a molecular signal (measurable biological change) of future lung cancer could already be present in blood many years before diagnosis,” Feng said.