Cholesterol transport protein emerges as possible target for Parkinson’s treatment

Parkinson's disease (PD) is a neurodegenerative condition that causes the progressive loss of dopamine-producing neurons in a brain region called the substantia nigra.

While there is currently no cure for the disease, some medications can help to manage its symptoms. Understanding how PD damages dopamine-producing neurons could help to develop new treatments that effectively slow down the disease’s progression.

Past studies have uncovered a link between PD and an accumulation of cholesterol in the brain. Attempts to slow down the disease by reducing cholesterol production, however, have had limited success so far.

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