Flavonoid found in citrus slows lung cancer cell growth in lab tests

Quercetin is found in citrus fruits, onions and buckwheat and is known for its anti-inflammatory properties. Now researchers at Universitätsklinikum Erlangen at Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) have investigated how the plant compound could help treat lung cancer.

Lung cancer is the most common form of cancer worldwide—no other cancer causes more deaths. Although there are various treatment options available, they do not work for all patients. Researchers in the Department of Molecular Pneumology at Universitätsklinikum Erlangen have now shown that quercetin acts on lung cancer cells at several sites.

“Many drugs against lung cancer target a single molecule,” explains Dr. Susetta Finotto. “Quercetin, by contrast, attacked at several points simultaneously in our experiments.” For the study, the researchers examined the effect of quercetin on lung cancer cells in the lab, on mouse lung sections and in living mice.

Sign up for Blog Updates