Human kidney organoids successfully integrated into pig kidneys in transplant study

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

This technology allows the organoids to be combined with pig kidneys outside the body and then transplanted back into the same animal to evaluate their viability. This breakthrough study, published in the journal Nature Biomedical Engineering, is a significant milestone in regenerative and personalized medicine. It paves the way for the use of kidney organoids derived from human stem cells in cell therapy clinical trials.

Led by Dr. Núria Montserrat, who was a principal investigator at IBEC at the time of the study and is now Minister of Research and Universities of the Government of Catalonia, this work is the result of over a decade of scientific research dedicated to regenerative medicine and organ bioengineering.

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