UC College of Engineering and Applied Science Distinguished Research Professor Chong Ahn and his students developed a “lab-on-a-chip” device that measures the stress hormone cortisol from a patient’s saliva. Knowing if a patient has elevated stress hormones can provide useful diagnostic information even if patients do not report feelings of anxiety, stress or depression in a standard mental health questionnaire.

Mental health disorders affect more than 400 million people around the world. Stress disorders such as anxiety and depression are among the leading causes of disability worldwide. Prolonged cortisol elevation is linked to numerous mental health disorders, including depression and anxiety.