Light therapy provides new hope for Alzheimer’s patients

Researchers have developed a new light technology that appears to improve cognitive function in Alzheimer's patients in clinical trials. The hope is that the idea can be developed into ordinary lamps that people can install to prevent the disease.

Researchers at DTU and UC Berkeley, together with spin-out company OptoCeutics, have invented a non-medical form of therapy that can improve brain activity: light-based deep brain stimulation that induces a specific type of brain wave that Alzheimer’s patients benefit from. An article on the technology is published in the journal PLOS One.

Clinical trials conducted by doctors at Zealand University Hospital in Roskilde have shown a beneficial effect in preliminary studies on people with Alzheimer’s where these gamma brain waves were induced: The results suggest that patients with mild to moderate Alzheimer’s experienced improved cognitive abilities in relation to, e.g., speech and memory. A study involving more participants is underway to confirm the results.

DTU Professor Paul Michael Petersen, one of the inventors of the technology, says that the idea for the device is based on research from MIT. Nearly 10 years ago, their research showed that when mice with Alzheimer’s were exposed to blinking lights, gamma brain waves were induced, which in turn reduced plaque caused by beta-amyloid proteins in the brain.

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