Since then, scientists have been fine-tuning this vaccine delivery system to make it more effective. A Yale research team has now developed a technology that improves both the power of mRNA vaccines and their effectiveness against a host of diseases.
The new technology offers the promise of expanding the reach of these vaccines, including for the prevention of other diseases, including cancer and autoimmune diseases.
The results of their study are published in Nature Biomedical Engineering.
Unlike traditional vaccines, which typically deliver an inactivated or weakened version of a virus to stimulate a person’s immune response, mRNA vaccines deliver genetic instructions that create a bit of a virus inside the individual’s cells. The cells then make the protein needed to create an immune response.