Neurotransmitter may help aggressive prostate cancer shut out immune cells from the start

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

“We already know that the immune system and cancers communicate with each other, which has led to transformative therapies for cancers that had once been thought of as untreatable,” said Dario C. Altieri, M.D., president and CEO, director of the Ellen and Ronald Caplan Cancer Center and Robert and Penny Fox Distinguished Professor at The Wistar Institute, and senior author of the study.

“This study reveals that cancer is also communicating with the nervous system, potentially opening the door to new therapies for cancers that currently lack effective therapeutic options.”

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