New AI tool can predict where glioblastoma is most likely to return after initial surgery

A new AI-based model can predict where glioblastoma is most likely to return after initial surgery, potentially giving doctors a chance to treat it before it becomes visible on MRI.

Glioblastoma is the most common malignant brain tumor in adults and the most lethal, with a median survival of about 17 months after diagnosis. Even after surgeons remove all visible tumor and patients receive follow-up treatment, the cancer almost always returns.

Now, researchers at UC San Francisco and the University of Michigan have developed an AI approach that can predict, with a high degree of accuracy, where the cancer is likely to recur first. In glioblastoma, most recurrences occur at or close to the tumor cavity.

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