New implant links insulin-producing cells to blood vessels, aiming to treat Type 1 diabetes

Researchers at McGill University and the Research Institute of the McGill University Health Center (RI-MUHC) have developed a novel device to transplant insulin-producing cells that integrates directly with existing blood vessels in the body.

“Insulin, discovered in Canada 100 years ago, has saved many lives, but it’s not a cure,” said Corinne Hoesli, study co-author and Associate Professor in the Department of Chemical Engineering. “We designed a device with a pre-formed network of artificial blood vessels that looks like a vascular bypass graft, except we introduced insulin-secreting cells into it.”

“This starts to look like a bona fide artificial organ,” she said, adding that a key element of success was interdisciplinary collaboration with researchers across Canada, including teams from Université Laval, the University of British Columbia, and Université de Montréal.

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