This discovery not only suggests alternative pathways for cell-to-cell communication but also identifies a potentially more effective therapeutic target for treating autoimmune diseases. Their results are published in Nature.
“The discovery of this receptor-free signal transduction underscores the value of exploratory science as a means to expand the lexicon of life,” said Jonathan Kagan, Ph.D., senior author and director of basic research and Shwachman Chair in Gastroenterology at Boston Children’s.