Osteoarthritis is the most common form of arthritis. It causes inflammation, stiffness, reduced mobility and sensory nerve pain. According to the World Health Organization, knee osteoarthritis affects more than 365 million adults worldwide and is one of the leading contributors to disability.

“For many patients with knee osteoarthritis, there is a real treatment gap today,” said Florian Nima Fleckenstein, M.D., deputy head of interventional radiology at Campus Mitte, Charité-Universitätsmedizin Berlin.

“Conservative measures such as intra-articular injections no longer provide sufficient relief, but joint replacement is not an option for medical or personal reasons.”