Programmable wound zipper adapts to complex skin injuries, improving healing in rats

To utilize flexible bioelectronic systems for wound healing, researchers designed the MSWZ. The MSWZ is made up of a mechanical metamaterial in a lattice structure that shrinks and responds like human skin, a reliable conductive layer, and a breathable, flexible encapsulation material.

A new study, published in Advanced Science, shows that a multi-axis stretchable wound zipper (MSWZ) is effective in closing complex wounds quickly, improving wound healing. The MSWZ uses programmable force that can be personalized via mobile application, enhancing patient comfort and compliance.

Current conventional approaches, such as sutures, cannot adapt to complex wound shapes and require health care professionals for their application. New alternatives, like temperature-responsive contractile dressings, are promising, yet can be unpredictable, compromised by environmental factors, and insufficient in their force to close a wound.

Flexible bioelectronic systems enable precise control of mechanical contraction, though they have not yet been used in wound healing.

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