Irvine, California-based Relief said it’s implant is the world’s first designed to both hemodynamically monitor and treat congestion in heart failure.

The procedures took place in the Republic of Georgia as part of a feasibility study evaluating the system’s safety. Dr. Tamaz Shaburishvili, Dr. Levan Sulakvelidze, and Dr. Gigi Shaburishvili performed the implants at Tbilisi Heart and Vascular Center with support from Dr. Alex Rothman, Professor of Cardiology at the University of Sheffield. The doctors reported patient discharges to their homes with their implanted system automatically syncing with the cloud nightly.

Relief’s system features a pressure-guided active valve implanted in the vena cava. It dynamically reduces cardiac preload and enhances renal vein flow on demand. The company says that the system integrates hemodynamic monitoring with an adaptive hemodynamic therapy into a single transcatheter implant. This introduces “a new paradigm” in heart failure with direct, personalized decongestion through a data-driven therapeutic implant.