Research points the way toward an exhaled-breath test for lung cancer

The foundational science to develop an exhaled-breath test for detection of lung diseases, including lung cancer, is underway, according to new research published by a laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI).

Two papers published by CDI Associate Member Olivier Loudig, Ph.D., and colleagues show that they have successfully collected, separated, and profiled lung biomarkers from human breath, and also developed animal models to expand their analyses and potentially identify key markers for early and non-invasive detection of metastatic lung tumors.

Significant work remains to be done to identify a range of biomarkers and prove that its accuracy can be clinically relevant for human patients, but the two publications have established the scientific roadmap as the CDI scientists continue their work toward that goal.

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