Researchers uncover brain-network dynamics in schizophrenia

Researchers at Georgia State University have identified a previously unknown aspect of schizophrenia that offers a new way to understand how the disorder affects large-scale brain coordination. In a new study, published in the journal Translational Psychiatry, researchers introduced a method for measuring how brain networks maintain balanced activity and recover when that balance is disrupted.

The approach revealed the brain’s ability to steer itself back toward balance after disturbances, and the findings suggest that people with schizophrenia experience more frequent imbalances in brain network activity and greater difficulty restoring that balance once it is lost.

“Our findings reveal that schizophrenia is not simply a disorder in which the brain falls out of balance more often,” said Sir-Lord Wiafe, a Georgia State doctoral candidate in computer science and first author of the study.

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