Scientists engineer nanostructured surfaces hostile to bacteria but friendly to cells

Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells.

Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells. They found that anodic porous alumina (APA) surfaces prepared using electrochemistry in concentrated sulfuric acid had unprecedented resistance to bacterial growth, but did not hamper cell cultures.

he work is published in the journal Langmuir.

The team’s technology promises to have a big impact on regenerative medicine, where high quality cell cultures without bacterial contamination may be produced without antibiotics.

Surfaces that resist bacterial contamination play a vital role in public health and our daily lives. While this might be achieved with powerful antibiotics and chemicals, this entails a negative environmental impact, health hazards, as well as the potential emergence of dangerous, antibiotic-resistant strains. We need alternative ways of controlling the spread of bacterial pathogens.

This is where nanostructured surfaces come in. In the early 2010s, it was shown that the naturally formed nanostructure on the wings of cicada and dragonfly wings can resist bacterial contamination.

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