Smarter tissue and organ repair thanks to next-gen hydrogel

A multidisciplinary team have built hydrogels built entirely from synthetic peptides so their properties can be precisely tailored through chemical design. By harnessing the power of collagen-inspired peptides and light-triggered chemistry, a University of Ottawa research team has engineered a customizable material with the potential to be a gamechanger for soft tissue repair, whether it's closing a surgical incision or sealing a traumatic wound.

In a compelling new study published in Advanced Functional Materials, the collaborative team demonstrates a new strategy for creating biomimetic, entirely peptide-based hydrogels that combine strength, adaptability, and biological compatibility. Unlike many existing biomaterials used as soft tissue adhesives, it doesn’t rely on any synthetic polymers which can trigger unwanted immune responses.

This streamlined approach makes it especially attractive for future biomedical applications, according to Dr. Emilio I. Alarcón, professor at the University of Ottawa Faculty of Medicine and scientist at the University of Ottawa Heart Institute.

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