Targeted radioactive therapy may help delay spread of recurrent prostate cancer

Adding the targeted radioactive drug 177Lu-PNT2002 to stereotactic body radiation therapy, or SBRT, may help keep recurrent prostate cancer under control longer than SBRT alone, according to new research led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

The team found patients who received the combination were less likely to develop widespread disease or hormone-resistant cancer, suggesting the treatment may offer benefits beyond delaying the initial return of the disease.

The findings, published in the journal European Urology, come from an updated analysis of the phase 2 LUNAR trial, which followed men for nearly three years after their prostate cancer had returned and was detected in a limited number of sites.

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