True Indicating Announces FDA Clearance of InstaTRU™, an Instant Biological Indicator for Steam Sterilization Cycles

TOLEDO, Ohio, Oct. 7, 2026 /PRNewswire/ -- True Indicating, LLC today announced they received FDA clearance of InstaTRU™, an instant biological indicator for steam sterilization cycles that provides results in just 20 seconds. Using spore-based technology, InstaTRU™ confirms the efficacy of a steam sterilization cycle without requiring an incubator or reader.

For dental practices and other healthcare facilities that rely on steam sterilization, delays in biological monitoring results delay the identification of sterilization cycle failures. True Indicating’s InstaTRU™ provides results in seconds, eliminating the risks inherent to the Mail-Back Program, and InstaTRU™’s web-based software efficiently records the results for compliance.

Biological Monitoring Without Incubation

InstaTRU™ uses a biological tablet and indicator solution to produce an easy-to-interpret visual result following steam sterilization. After exposure, a staff member retrieves the BI, accesses the tablet, and applies one drop of indicator solution. A red result indicates a failed cycle, while an off-white result indicates a pass.

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