A joint research team led by C. Justin Lee, director of the Center for Memory and Glioscience at the Institute for Basic Science, and Ha Yoon, a professor at Yonsei University College of Medicine, developed TRANsCre-DIONE, a system designed to selectively convert reactive astrocytes at an injury site into neurons.
The findings, published in the journal Experimental & Molecular Medicine, offer a potential new direction for spinal cord repair, although the approach has not been tested as a treatment in humans.