Zavation Medical Products Announces First Implantations of Varisync® ALIF NanoPrime™

FLOWOOD, Miss., Nov. 15, 2025 /PRNewswire/ -- Zavation Medical Products, LLC ("Zavation"), a leading innovator in spinal device technology, announces the first successful implantations of the Varisync® ALIF NanoPrime™ System, a next-generation stand-alone ALIF system featuring Zavation's proprietary titanium ion bond technology.

Dr. Steve Zhou successfully performed a two-level anterior lumbar fusion using the NanoPrime ALIF to treat a patient with a L4-L5 Grade 1 spondylolisthesis and severe L5-S1 spondylosis. Post-operatively, the patient reported an improvement in symptoms.

“The NanoPrime ALIF cage offered excellent radiographic visibility and the potential to lead to positive surgical outcomes,” said Dr. Steve Zhou. “Its softer modulus compared to pure titanium reduces the risk of subsidence, while the titanium-bonded surface promotes solid fusion and eliminates my concerns of fibrous union.”

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