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Novel biomarker catches aging cells in the act

Mayo Clinic researchers have identified interleukin-23 receptor (IL-23R) as a significant biomarker of cellular senescence and aging in both mice and humans. Experiments show that IL-23R levels in the bloodstream increase with age and can decrease, reflecting senescent cell clearing, with senolytic therapies.

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Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes

Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year. Damage caused by these diseases is particularly difficult to repair, since the heart has minimal ability to regenerate itself. But what if we could reprogram the body’s own cells to restore damaged tissue? This question has been tackled by scientists at Korea University, led by Dr. Myeong-Hwa Song.

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