MedTech News
.................... by Andrew Celentano

Affera™ momentum continues as Medtronic announces CE Mark in Europe and U.S. IDE first cases for Sphere-360™ PFA catheter to treat paroxysmal atrial fibrillation
First-of-its-kind, rotation-free single-shot PFA catheter supported by strong safety and efficacy data adds to the groundbreaking Affera family of technologies in Europe

Cancer’s secret safety net
Researchers uncover a hidden mechanism that allows cancer to develop aggressive mutations.

Spinal Resources Strengthens IP Portfolio with New Bezier Rod Patent
The patent’s focus on a constant-slope transition ensures a gradual and predictable stiffness profile

Advancing the realization of oral insulin using novel peptide technology
For more than a century, oral insulin has been considered a “dream” therapy for diabetes, hindered by enzymatic degradation in the digestive tract and the absence of a dedicated intestinal transport mechanism. Consequently, many patients must rely on daily insulin injections, which can significantly reduce their quality of life.

Tiny molecules called tRNA halves may contribute to prostate cancer cell growth
Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves.

Regenerating lost lymph nodes with bioengineered tissues
The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences.

Microbes living in our mouths could hold the key to obesity prevention
Scientists may have found a new way to spot early signs of obesity, which could lead to novel prevention strategies. A study published in the journal Cell Reports has discovered that people living with obesity have a distinct set of microbes in their mouths compared to people at a healthy weight.

Iron supplements restore muscle strength in mouse model of muscular dystrophy
Researchers at Kumamoto University have demonstrated that iron supplementation can significantly alleviate muscle pathology and functional decline in a mouse model of facioscapulohumeral muscular dystrophy (FSHD), a rare genetic muscle disease for which no effective treatment currently exists.