Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques, the team has shed light on the cell signaling mechanisms guiding differentiation in stem cells in the developing teeth, offering key insights for future regenerative dental therapies.
New research from the MRC Laboratory of Medical Sciences (LMS) provides a powerful, scalable method for finding treatments for rare genetic diseases using tiny, transparent worms.
Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos. The research is published in Nature Communications.
UK researchers said Wednesday they had slowed the progression of the fatal neural condition Huntington’s disease for the first time with a groundbreaking new gene therapy.
Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes.
Researchers from the Department of Biomedical Engineering at UNIST and the Center for Genomic Integrity at the Institute for Basic Science (IBS) have announced an advance in cancer gene therapy.
Researchers at Dana-Farber Cancer Institute have developed a diagnostic tool that could transform the way acute leukemia is identified and treated. The tool, called MARLIN (Methylation- and AI-guided Rapid Leukemia Subtype Inference), uses DNA methylation patterns and machine learning to classify acute leukemia with speed and accuracy
Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.
Researchers from the University of Birmingham’s Bladder Cancer Research Center have used a new method to detect chemical changes in the DNA in an individual’s urine sample; epigenetic changes, called methylation.
Researchers in Berlin have used base editing to repair mutations that cause the kidney disorder ADPKD in cells from both mice and humans. In mice, a team led by Michael Kaminski was able to ease a key symptom of the difficult-to-treat disease.