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How heart failure reshapes bone marrow to create inflammation-related immune memory

Heart failure (HF) is a condition in which the heart is not able to pump blood effectively. However, its effects go beyond pumping and circulation. HF is also known to cause a lasting form of innate immune memory in stem cells that synthesize blood and progenitor cells that are present in the bone marrow (BM). This can result in the production of immune cells that promote inflammation and worsen heart function. However, the exact mechanism of this process remained unclear.

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Moldable gel controls bleeding and supports bone repair in preclinical tests

A research team from the Faculty of Dentistry at The University of Hong Kong (HKU), working in collaboration with Su Ryon Shin’s group at Brigham and Women’s Hospital, Harvard Medical School, has advanced and preclinically validated a shape-adaptive hydrogel designed for challenging clinical trauma scenarios involving severe bleeding, irregular bone defects and comminuted fractures.

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Two studies link elevated ear protein levels in blood to tinnitus

When Dr. Kourosh Parham conceived a first-of-its-kind blood test for tinnitus, he knew further research was needed to confirm a link between a unique ear protein and the common hearing disorder. To validate his theory, the professor of surgery at UConn Health (UCH), Division of Otolaryngology-Head & Neck Surgery, teamed up with fellow UCH physician-scientists to conduct two clinical trials.

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True Indicating Announces FDA Clearance of InstaTRU™, an Instant Biological Indicator for Steam Sterilization Cycles

TOLEDO, Ohio, Oct. 7, 2026 /PRNewswire/ — True Indicating, LLC today announced they received FDA clearance of InstaTRU™, an instant biological indicator for steam sterilization cycles that provides results in just 20 seconds. Using spore-based technology, InstaTRU™ confirms the efficacy of a steam sterilization cycle without requiring an incubator or reader.

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Resivant Medical Receives U.S. Patent Protecting Novel Single-Lever, Single-Handed Applicator at the Core of the Cutiva™ PLUS Skin Closure System

AKRON, Ohio, Sept. 22, 2026 /PRNewswire/ — Resivant Medical announced today that the U.S. Patent and Trademark Office has issued Patent No. 12,678,148, covering the novel single-lever, single-handed applicator design at the core of the Cutiva™ PLUS Skin Closure System. The patent protects the mechanism that allows clinicians to start, control, and stop the flow of adhesive using a single lever, without repositioning the hand or device.

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