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Decoding inflammatory bowel disease—on a chip

In the study, a multi-disciplinary research team led by Wyss Institute at Harvard University Founding Director Donald Ingber, M.D., Ph.D., worked with clinicians at McGill University in Canada and Massachusetts General Hospital who provided IBD and healthy tissue biopsies from the colon region of the same patients to create donor-specific microfluidic organ-on-a-chip (Organ Chip) models of colon that replicate major hallmarks of IBD in vitro in an unprecedented way.

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