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Custom-designed protein receptors help T cells target solid tumors more effectively

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment. But while they’ve delivered impressive results against certain blood cancers, they’ve struggled to make an impact in solid tumors, such as those in the breast, lung, and prostate.

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Ultrasound probe can image an entire organ in 4D

For the first time, a team of Inserm researchers from the Physics for Medicine Institute (Inserm/ESPCI Paris-PSL/CNRS) has succeeded in mapping the blood flow of an entire organ in animals (heart, kidney and liver) with great precision, in four dimensions: 3D and time.

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