Gene map reveals how transplanted stem cells repair damaged heart muscle

Researchers led by Assistant Professor Lynn Yap of the Lee Kong Chian School of Medicine at Nanyang Technological University, Singapore, have uncovered new insights into how unspecialized cells, also known as stem cells, develop and mature into heart muscle cells. The findings could pave the way for new treatments for heart disease.

Published in Nature Cardiovascular Research, the study is one of the first to track the activity of genes at different points in the regeneration process.

The scientists also found that a protein called Midkine can repair damaged blood vessels and may help improve recovery after heart attacks.

Getting to the heart of the matter

Heart disease is one of the leading causes of death globally, accounting for a third of deaths worldwide. In Singapore, about 22 people die from heart disease every day.

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