Menopause-associated estrogen loss makes the burden of this disease higher in women globally, as 1 in 3 women over age 50 is at risk of suffering an osteoporosis-related fracture.
A recent study published in Cell explored a novel stem cell therapy for advanced osteoporosis that cleverly uses a patient’s own stem cells as a biological targeting tag, binding to blood vessels in the bone marrow and guiding the infused stem cells directly to damaged bone tissue.
In a first-in-human trial, 10 women over 50 with advanced osteoporosis received an infusion of the specially engineered repair cells via a single intravenous (IV) drip.