Placing battery tech directly on tissue to deliver lithium ions for targeted pain relief

A new study from the University of Chicago taps an ingredient most often used in the lithium-ion batteries that power our devices to open new avenues in biomedical technology. Lithium plays vital roles in the body, but taking it orally can have unwanted side effects—so a pair of UChicago chemistry labs teamed up to find a way to deliver lithium only to the exact places where it's needed.

Their study, published in Nature Materials, could be the foundation for future biomedical technologies to treat pain and disease.

“On the surface, it sounds like a crazy idea to place a lithium-ion battery electrode onto a living tissue, but the results we had are very promising,” said Zhe Cheng, first author of the study and a graduate student at UChicago.

“Lithium calms nerve activity, which makes it potentially very useful—we have many biomedical approaches to precisely stimulate nerves, but less to dampen them, which is what is needed for pain relief and other disorders.”

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