Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Tracking down senescent cells, which accumulate as we age, could help diagnose age-related disorders and guide researchers working on new treatments.

As we age, some of the cells in our body enter a state of senescence, in which they stop dividing but do not die. Those senescent cells can contribute to age-related disorders such as cancer, tissue degeneration, and inflammatory diseases.

In an advance that could lead to better ways to diagnose and treat those diseases, MIT researchers have developed a noninvasive way to detect biomarkers of senescence. Their method is based on Raman microscopy, which can reveal the biochemical composition of cells without harming them.

Sign up for Blog Updates