MedTech News
.................... by Andrew Celentano
Hidden immune cells in the lung could lead to better flu vaccines
Most current flu vaccines—especially those given by injection—do not reliably build strong immune memory in the airways, leaving a gap in protection against initial infection and transmission.
Cancer’s malignant remote control: How tumors reprogram liver fat metabolism to disarm immune cells
In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century explored the genetic aberrations and microenvironmental peculiarities of tumors and their constituent cells.
A ‘one-two punch’ against aggressive breast cancer could offer an alternative to chemotherapy
Triple-negative breast cancer (TNBC) has a frustrating ability to adapt. Although this aggressive form of breast cancer can initially respond well to chemotherapy, cancer cells often find ways to survive, allowing the disease to return and become resistant to treatment.
Stress proteins actively sustain joint inflammation in osteoarthritis, study finds
Why do some joints remain chronically inflamed in osteoarthritis and other rheumatic diseases?
RevMed receives early FDA approval for ‘groundbreaking’ pancreatic cancer drug
The FDA granted the approval of Revolution Medicines’ daraxonrasib, now to be known as Rasonque, in pancreatic adenocarcinoma 6.5 months ahead of deadline.
Cell therapy substantially reduces severe rheumatoid arthritis in first clinical trial
Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients’ own immune cells, could also help cure autoimmune diseases.
Immune cells that drive harmful autoantibody responses after COVID-19 identified
When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader. But in some people infected with SARS-CoV-2, the virus that causes COVID-19, the immune response goes awry, producing autoantibodies—antibodies that mistakenly attack the body’s own tissues.
New combination therapy shows promise in metastatic pancreatic cancer
Results from an early-stage clinical trial, published in Nature Communications, showed encouraging outcomes among patients with newly diagnosed cancer whose tumors had spread to distant organs.