Researchers from the Department of Biomedical Engineering at UNIST and the Center for Genomic Integrity at the Institute for Basic Science (IBS) have announced an advance in cancer gene therapy.
Researchers at Dana-Farber Cancer Institute have developed a diagnostic tool that could transform the way acute leukemia is identified and treated. The tool, called MARLIN (Methylation- and AI-guided Rapid Leukemia Subtype Inference), uses DNA methylation patterns and machine learning to classify acute leukemia with speed and accuracy
Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.
Researchers from the University of Birmingham’s Bladder Cancer Research Center have used a new method to detect chemical changes in the DNA in an individual’s urine sample; epigenetic changes, called methylation.
Researchers in Berlin have used base editing to repair mutations that cause the kidney disorder ADPKD in cells from both mice and humans. In mice, a team led by Michael Kaminski was able to ease a key symptom of the difficult-to-treat disease.
A researcher at the Hackensack Meridian Center for Discovery and Innovation (CDI) and physician-scientist colleagues from Hackensack Meridian Health have shown how a critical pathway is fundamental to the immune system.
Tulane University researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based screenings for the world’s deadliest infectious disease.
Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing “copilot” supported by AI to help researchers—even those unfamiliar with gene editing—generate designs, analyze data and troubleshoot design flaws.
Advance from SMART will help to better identify disease markers and develop targeted therapies and personalized treatment for diseases such as cancer and antibiotic-resistant infection.
Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or cure for MSMDS.