In a study published in Nature Communications, the researchers found that the EXO1 gene is overexpressed in 20% to 30% of breast and ovarian cancers as well as in melanoma, testicular, cervical, and hepatobiliary cancers, which develop in the liver, gall bladder, and bile duct
Researchers at Penn State have developed a reusable material designed to solve both problems at once. The material is a thermoreversible semiconducting ionic biogel, meaning it becomes liquid when gently heated so it can move through hair and reach the scalp, then returns to a stable gel as it cools, keeping its conducting and semiconducting character.
Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children’s, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods—and these organoids grow their own nerve cells.
A team of researchers from Carnegie Mellon University, in collaboration with Cleveland Clinic’s Cardiovascular Innovation Research Center, has developed an artificial intelligence (AI) system capable of interpreting some of the most complex heart scans in medicine, cardiac magnetic resonance imaging (MRI), without the need for manually labeled training data.
We were expecting the two components, the cells and the microenvironment, to evolve in lockstep. They did not,” said co-senior study author Marina Pasca di Magliano, Ph.D., Maud T. Lane Professor of Surgical Immunology and co-director of the Rogel and Blondy Center for Pancreatic Cancer at the University of Michigan.
A research team led by Fanyuan Yu from Sichuan University, China, has now discovered one of the mechanisms of DPSC senescence and identified a potential strategy to counter it.
Researchers with the James P. Allison Institute at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.
Researchers have identified a key protein that may help failing hearts regain function, offering new insight into why some hearts recover while others do not.
The study, conducted by researchers at Baylor College of Medicine and Texas Children’s Hospital, appeared in the American Journal of Human Genetics.
In the study, a multi-disciplinary research team led by Wyss Institute at Harvard University Founding Director Donald Ingber, M.D., Ph.D., worked with clinicians at McGill University in Canada and Massachusetts General Hospital who provided IBD and healthy tissue biopsies from the colon region of the same patients to create donor-specific microfluidic organ-on-a-chip (Organ Chip) models of colon that replicate major hallmarks of IBD in vitro in an unprecedented way.