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- NOVEL DISCOVERIES

Ingestible pill developed to diagnose intestinal disorder

Researchers led by investigators at Mass General Brigham and Massachusetts Institute of Technology have validated an ingestible capsule in preclinical models for the diagnosis of acute mesenteric ischemia, a condition caused by blocked or reduced blood flow to the intestines. The research is published in Science Robotics.

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Tears could open new avenue for diagnosing and monitoring eye and neurodegenerative diseases

Ocular fluids provide a window into the health of the eye and the development of various pathologies. However, their study usually involves invasive techniques. “A wide range of eye diseases are being investigated, but the methods for obtaining aqueous humor and vitreous humor, the fluids inside the eye, are highly invasive, which limits their applicability in routine clinical practice,” explains Marta San Roque, Ph.D. student in the Innovation in Vesicles and Cells for Application in Therapy (IVECAT) Group at the Germans Trias i Pujol Research Institute (IGTP).

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New technique involving metal carbonyl allows researchers to track chemotherapy drugs inside cells

Scientists have made significant progress in developing cancer therapies that help patients across cancer types. However, they face limitations in determining the results of drug effectiveness, as well as ensuring even distribution among all cancer cells because of the highly compact nature of tumors. Researchers are working to change that by giving chemotherapy drugs a kind of chemical “signal” that allows them to be tracked inside of cells.

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iNPLANT LLC Launches XL Funnel: The First “No-Touch” Delivery System for Large Breast Implants

ALLENDALE, N.J., Oct. 22, 2025 /PRNewswire/ — iNPLANT LLC, a leader in surgical innovation, today announced the release of the iNPLANT XL Funnel, a next-generation surgical device designed for the insertion of large breast implants (800cc–1500cc) using the “No-touch” surgical technique. The XL Funnel is the only device engineered specifically for this size range, addressing a critical unmet need in reconstructive and aesthetic breast surgery.

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Ampa Launches Nationwide Rollout of Portable FDA-Cleared Brain Stimulation System Following $8.5M Oversubscribed Funding Round

PALO ALTO, Calif., Oct. 22, 2025 /PRNewswire/ — Four months after emerging from stealth with FDA clearance of the Ampa One system and an oversubscribed $8.5 million round led by Nexus NeuroTech Ventures, Ampa today announced its nationwide rollout. This milestone marks a major step in bringing advanced, non-invasive brain stimulation to patients across the country and brings Ampa’s total funding to $18 million.

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Researchers find a new targeted approach to shut down prostate cancer growth

Prostate cancer relies on genetic “switches,” called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers. They further implicate two proteins, p300 and CBP, that add these marks, and along with the androgen receptor, turn on enhancers and promote prostate cancer growth.

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