Researchers have developed a 3D map of an ovary for the first time, enabling a deeper understanding of how and when oocytes — immature eggs — are activated. Published in the journal Nature Aging, the team believes their findings have important implications for human reproductive health, as well as opening the door to future studies.
The FDA has given the go-ahead to Ultragenyx’s rebisufligene etisparvovec—now to be marketed under the brand name Fayuvi—for the treatment of Sanfilippo syndrome type A, an ulta-rare, progressive neurological condition in children.
The 62-patient multicentre trial is evaluating a nanoparticle-based platform designed to help identify sentinel lymph nodes in gastric and oesophageal cancer surgery.
Gut instinct, gut feeling or gutting it out—what exactly is the human gut? It’s the workhorse of the digestive system and home to a vast, dynamic community of microorganisms that influence human health. In fact, the human body contains roughly equal numbers of nonhuman (microbial) and human cells.
There is no cure for HIV. While scientists have made considerable progress in controlling the infection, patients still must take daily antiretroviral medication for the rest of their lives. Results from a clinical trial led by Rockefeller, Imperial College London, and the University of Oxford (RIO) have offered a new strategy, suggesting that just one or two doses of broadly neutralizing antibodies (bNAbs) can suppress the virus long term, keeping it at undetectable levels for months and even years.
The rete ovarii (RO) is a small structure attached directly to the ovary that has largely faded from view since it was first described more than a century ago. Its name comes from the Latin word for “network,” referring to the interconnected tubes and channels that make up the structure, according to the National Cancer Institute.
A simple method involving local anesthesia in the uterus can reduce pain during IUD insertion, according to a new study from Karolinska Institutet, published in the journal JAMA. The method also increased the proportion of women who found the procedure tolerable. The results may encourage more women to choose an IUD as a contraceptive method.
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are the clinical gold standards for screening blood sugar levels, yet they provide only static snapshots that fail to reflect the highly dynamic and heterogeneous nature of metabolic impairment. However, continuous glucose monitoring (CGM) is reshaping our understanding of these levels. While the medical community already has begun capitalizing on CGM for diabetes management, a new study has the potential to change current clinical practices for cardiovascular disease risk stratification in individuals without diabetes.
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified candidate treatment targets and potential prognostic markers for high-grade glioma, an aggressive brain cancer, in children, adolescents and young adults.
A new study published in the journal npj Breast Cancer demonstrates that an artificial intelligence (AI) model offers more accurate predictions of recurrence risk in patients with early-stage breast cancer than the widely used 21-gene Recurrence Score. This research, conducted by a team from the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and Caris Life Sciences, specifically targets hormone receptor-positive (HR+) and HER2-negative disease, the most common subtype of breast cancer, which accounts for about half of all breast cancer cases in the United States.