Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.
Their study yielded hundreds of “cryptic” peptides that are found only on pancreatic tumor cells and could be targeted by vaccines or engineered T cells.
New Liquid Biopsy Technology Offers Hope in Diagnosing One of the Deadliest Cancers at an Early Stage
Two meters of DNA is crammed into the nucleus of every human cell. Bin Zhang wants to know how gene expression works in this minuscule space.
The research team, led by Professor Minee L. Choi from the Department of Brain and Cognitive Sciences, in collaboration with University College London (UCL) and the Francis Crick Institute, discovered that the RNA-editing enzyme ADAR1 plays an important role in controlling immune responses in astrocytes, glial cells that trigger protective reactions in the brain, and demonstrated that this mechanism is critically involved in the progression of Parkinson’s disease.
Researchers from Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions of our DNA, which make up the vast majority of the human genome.
Even though the virus was first discovered in laboratory monkeys in 1958, the original source came from a squirrel.
Findings reveal opportunities for new treatments of Parkinson’s and related neurodegenerative disorders
The Greenland shark likes to stick around, with some estimates suggesting a lifespan of more than 500 years – and a new study of the shark’s DNA has given researchers vital clues to the secret of its longevity.
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.