MedTech News:

Andrew Celentano

Drug-coated balloons could offer an alternative to permanent heart stents for some patients

Thousands of heart patients could be treated without having a metal stent permanently implanted in their arteries—according to research from the University of East Anglia (UEA). A major analysis of more than 7,800 patients found that a newer treatment using drug-coated balloons performed just as well as conventional stents at preventing heart attacks and cardiovascular deaths.

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How heart failure reshapes bone marrow to create inflammation-related immune memory

Heart failure (HF) is a condition in which the heart is not able to pump blood effectively. However, its effects go beyond pumping and circulation. HF is also known to cause a lasting form of innate immune memory in stem cells that synthesize blood and progenitor cells that are present in the bone marrow (BM). This can result in the production of immune cells that promote inflammation and worsen heart function. However, the exact mechanism of this process remained unclear.

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Lab-grown tumors reveal immune cells capable of killing small cell lung cancer

Researchers have uncovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, the most aggressive form of the disease globally. Published in Cancer Cell, the WEHI study found patients with higher levels of these cells lived longer, uncovering a hidden immune defense that could be exploited to attack these hard-to-treat tumors.

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Moldable gel controls bleeding and supports bone repair in preclinical tests

A research team from the Faculty of Dentistry at The University of Hong Kong (HKU), working in collaboration with Su Ryon Shin’s group at Brigham and Women’s Hospital, Harvard Medical School, has advanced and preclinically validated a shape-adaptive hydrogel designed for challenging clinical trauma scenarios involving severe bleeding, irregular bone defects and comminuted fractures.

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