MedTech News
.................... by Andrew Celentano

Scientists find the gene that drives T-cell exhaustion, revealing new strategy to improve immune responses
Immunotherapy, which uses a patient’s immune system to treat disease, has increased survival for some adults and children with cancer. However, it has had limited success against many pediatric solid tumors, in part because T cells can become functionally impaired or “exhausted.” St. Jude Children’s Research Hospital scientists published results in Nature showing that the gene ZMYND8 is a major regulator of CD8+ T-cell exhaustion.

Solving Alzheimer’s with math? Researcher explores the possibilities
What can mathematics reveal about Alzheimer’s disease? Mississippi State University associate professor Shantia Yarahmadian is using mathematical modeling to examine how common metals may influence a protein that forms plaque associated with Alzheimer’s disease—and how potential therapies could alter these processes.

Enzyme USP15 present a promising new target for ovarian cancer treatment
Ovarian cancer is often diagnosed after it has already spread to other parts of the body, at which point the five-year survival rate is under 30%.

Portable device delivers rapid testing for mosquito-borne viruses
With a lot of ingenuity, some creative engineering and a few off-the-shelf items, a University of Florida team led by a virologist and an engineer has created an inexpensive, quick and accurate handheld device that can detect seven mosquito-borne illnesses

Neurotransmitter may help aggressive prostate cancer shut out immune cells from the start
A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

Experimental gene-silencing therapy offers hope for hepatitis B cure
Chronic hepatitis B is a long-lasting condition caused by the hepatitis B virus (HBV) that affects about 240 million people worldwide. Current antiviral treatments are designed to keep the virus under control, but they are not a cure, and medications are usually taken indefinitely.

Intuitive expands push into cardiac market with CE mark
After de-emphasizing heart surgery for decades due to limits with its earlier platforms, the surgical robot maker is eyeing the large market in cardiovascular disease treatment.

FDA grants breakthrough designation to Glytec’s Glucommander Pediatrics
The proposed prescription-only product would be separate from Glytec’s existing Glucommander technology.