MedTech News
.................... by Andrew Celentano

Space-grown glioblastoma organoids could help advance brain cancer treatments
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and is one of the most aggressive and deadly forms of cancer. It is difficult for surgeons to fully remove GBM because it often has microscopic “tentacles” that extend from the tumor into healthy brain tissue. GBM is also hard to treat because it creates an immunosuppressive microenvironment that helps the cancer evade immune attack and resist therapy.

Contrario Medical Receives FDA 510(k) Clearance for Cyperus Sperm Separation Device
Single-use device prepares motile sperm for IVF, ICSI and IUI, giving fertility labs the next evolution in sperm separation technology with advanced capabilities.

MIT engineers create nanoparticles for delivering personalized cancer vaccines
The particles carry a customized dose of cancer antigens that can provoke a strong immune response against tumors.

FDA expands approval of Instylla’s Embrace HES for arterial bleeds
Data supporting the expanded clearance came from the HALT study involving 130 patients.

Cholesterol-sharing mechanism points to potential new target for pancreatic cancer treatment
Fox Chase Cancer Center researchers identified a potential therapeutic target for pancreatic cancer after showing that tumor growth can be slowed and immune suppression can be reduced in preclinical trials by blocking a particular protein, called anoctamin 6 (ANO6).

First patient undergoes pioneering stem-cell treatment for Parkinson’s
A patient has undergone pioneering stem-cell therapy to treat Parkinson’s disease, the Japanese drugmaker behind the treatment said on Friday, in a world first following its conditional approval in the country.

Cancer-promoting proteins may make tumors easier to spot… but also help them evade immune attack
The immune system may recognize a cancer cell and still fail to destroy it. In a recent study, researchers at Hiroshima University and their international collaborators found that hyperactive YAP and TAZ (YAP/TAZ), two cancer-promoting proteins, were associated with genomic instability that may make cancer cells more recognizable to the immune system, while also increasing PD-L2, which helps the cells suppress T-cell attack.

New swab test could spare some women a painful biopsy for endometrial cancer
A simple vaginal swab may one day help women with abnormal bleeding learn whether they have endometrial cancer without first going through a painful biopsy.