MedTech News
.................... by Andrew Celentano

DNA repair protein gene gone rogue may unlock new cancer treatments
In a study published in Nature Communications, the researchers found that the EXO1 gene is overexpressed in 20% to 30% of breast and ovarian cancers as well as in melanoma, testicular, cervical, and hepatobiliary cancers, which develop in the liver, gall bladder, and bile duct

Thermoreversible biogel may solve a hairy problem for wearable brain-monitoring systems
Researchers at Penn State have developed a reusable material designed to solve both problems at once. The material is a thermoreversible semiconducting ionic biogel, meaning it becomes liquid when gently heated so it can move through hair and reach the scalp, then returns to a stable gel as it cools, keeping its conducting and semiconducting character.

3D-printed trays help human gut organoids self-build nerves and mature twice as fast
Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children’s, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods—and these organoids grow their own nerve cells.

Zimmer Biomet gets expanded FDA nod for Rosa robotic shoulder system
Zimmer Biomet (NYSE:ZBH) announced today that it received FDA 510(k) clearance for an advanced version of its Rosa Shoulder System.

Wearable knee robot could help children with muscle weakness
Yanggang Feng and colleagues designed a lightweight (0.96 kg) wearable knee robot to assist isokinetic training for children with SMA type II, an intermediate form of the condition. In a clinical trial, they tested outcomes in six children (aged 6–10 years old) who could not stand from a seated position without assistance.

AI unlocks cardiac MRI reading without manual labels, beating general models by 35%
A team of researchers from Carnegie Mellon University, in collaboration with Cleveland Clinic’s Cardiovascular Innovation Research Center, has developed an artificial intelligence (AI) system capable of interpreting some of the most complex heart scans in medicine, cardiac magnetic resonance imaging (MRI), without the need for manually labeled training data.

Study sheds light on how early pancreas lesions become cancerous
We were expecting the two components, the cells and the microenvironment, to evolve in lockstep. They did not,” said co-senior study author Marina Pasca di Magliano, Ph.D., Maud T. Lane Professor of Surgical Immunology and co-director of the Rogel and Blondy Center for Pancreatic Cancer at the University of Michigan.

Stem cells at the root of tooth aging point to possible treatment
A research team led by Fanyuan Yu from Sichuan University, China, has now discovered one of the mechanisms of DPSC senescence and identified a potential strategy to counter it.