MedTech News
.................... by Andrew Celentano

Experimental immunotherapy clears harmful artery cells, reducing plaque in mice
Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart disease.

Anticipating aging-related mental decline using saliva samples and AI
As humans age beyond early adulthood, their physical and mental functions tend to slowly worsen over time. One of the most common sources of severe mental decline in older adults are neurodegenerative diseases, conditions characterized by the progressive loss of neurons in the brain or peripheral nervous system.

Engineered micro scaffolds show promise for helping people recover from severe muscle loss
When a car accident or athletic injury destroys more than 20% of a muscle’s mass, the body faces a problem it often can’t heal fully on its own. Without intervention, scar tissue fills the injury site and can leave patients with permanent weakness and limited mobility.

Researchers discover genetic ancestry is a critical component of assessing head and neck cancerous tumors
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).

RNA therapy may be a solution for infant hydrocephalus
Hydrocephalus is a life-threatening condition that occurs in about 1 in 1,000 newborns and is often treated with invasive surgery. Now, a new study offers hope of preventing hydrocephalus before it even occurs. The paper is published in the journal Molecular Therapy.

Pleasure and pain: Tiny worm reveals secret to protecting skin sensations
A tiny roundworm has helped University of Queensland scientists uncover minuscule structures in skin tissue that may protect the body’s ability to feel temperature, touch and pain. The research is published in Science Advances.

AI tool predicts six-month risks for cancer patients after heart attack
Cancer patients who suffer a heart attack face a dangerous mix of risks, which makes their clinical treatment particularly challenging. As a result, patients with cancer have been systematically excluded from many clinical trials and available risk scores. Until now, doctors had no standard tool to guide treatment in this vulnerable group.

Designing the future of metabolic health through tissue-selective drug delivery
Founded by three MIT alumni, Gensaic uses AI-guided protein design to deliver RNA and other therapeutic molecules to specific cells or areas of the body.