MedTech News
.................... by Andrew Celentano

Tau’s surprise birthplace offers a clue to how Alzheimer’s tangles begin
Where and how does an Alzheimer’s tangle begin? A new study by neuroscientists at Columbia University challenges a long-held assumption about the source of toxic tau proteins, which form neurofibrillary tangles and are closely linked to memory decline in Alzheimer’s disease.

Mini-tumors reveal new drug combinations for liver cancer
Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically search for new treatment options. They tested more than 1,600 compounds using these organoids and used the results to develop promising drug combinations.

Lab-grown tissue reveals how inflammation may drive heart relaxation failure
Lab-grown tissues engineered from stem cells reprogrammed from human cells, called human induced pluripotent stem cells (hiPSCs), are rapidly emerging as a more reliable and accessible model in medical research.

ECG-based AI algorithm could improve detection and prediction of heart diseases
Now, scientists at Scripps Research have built a new AI model to improve detection and prediction of various heart diseases, which may be particularly useful in settings with limited labeled data or fewer available ECG leads

Blocking a microRNA reverses deadly lung disease in multiple models
Researchers blocked a naturally occurring molecule to reverse pulmonary arterial hypertension in preclinical models, a finding that could point to a new treatment approach for people with a rare and often fatal lung disease.

Powerful new tool reveals potential ‘goldmine’ of cancer targets hidden in ‘junk DNA’
A QIMR Berghofer-led team has developed a powerful tool to explore and understand the mysterious workings of the vast region of the human genome once dismissed as “junk DNA,” discovering thousands of molecules that could hold the key to new precision cancer treatments.

CergenX achieves CE Mark for pioneering AI technology designed to transform newborn brain assessment
Irish medtech company reaches major regulatory milestone for AI-powered technology providing rapid, objective insights into newborn brain activity

FibroBiologics Announces Issuance of New U.S. Patent for the Treatment of Degenerative Disc Disease Using Fibroblast Conditioned Media
Newly Issued Patent Covers Methods of Promoting Disc Regeneration Using Components Derived from Stimulated Fibroblasts