Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic acid—compromises both the body’s normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

Researchers from the Max Planck Institute for Mathematics in the Sciences Leipzig, Germany, the Institute of Mathematical Sciences in Chennai, India, and colleagues demonstrate how mathematical techniques from topological data analysis (TDA) can provide a new, multiscale perspective on brain connectivity.

Two proteins found on the surface of motor neurons in the brain may be essential in the progression of Parkinson’s disease, according to new Yale School of Medicine (YSM) research.

A research team from the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has demonstrated for the first time in non-human primates that auditory stimulation at 40 Hz significantly elevates β-amyloid levels in the cerebrospinal fluid (CSF) of aged rhesus monkeys, with this effect persisting for over five weeks.

A new international study has demonstrated that Alzheimer’s disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.